LEVEL 4 L02AE02

ATC

Δραστικές

LEUPRORELIN

Φάρμακα

  • DRUGBANK - Leuprolide
  • indication:

    For treatment of prostate cancer, endometriosis, uterine fibroids and premature puberty

  • pharmacology:

  • mechanism:

    Leuprolide binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion.

  • toxicity:

  • absorprion:

  • halflife:

    ~3 hours

  • roouteelimination:

  • volumedistribution:

    * 27 L [intravenous bolus administration to healthy male volunteers]

  • clearance:

    * 8.34 L/h [healthy male receiving a 1-mg IV bolus]