For treatment of heparin-induced thrombocytopenia
Inhibits the action of thrombin by binding both to its catalytic site and to its anion-binding exosite.
25 min (in normal conditions)
Angiomax is cleared from plasma by a combination of renal mechanisms and proteolytic cleavage
* 3.4 mL/min/kg [Normal renal function] * 3.4 mL/min/kg [mild renal function] * 2.7 mL/min/kg [moderate renal function] * 2.8 mL/min/kg [severe renal function] * 1 mL/min/kg [Dialysis-dependent patients]