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Alcaftadine
- indication:For the prevention of itching associated with allergic conjunctivitis.
- pharmacologypharmacology:
- mechanism: Alcaftadine is a H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. Decreased chemotaxis and inhibition of eosinophil activation has also been demonstrated.
- toxicity:
- absorprion:
- halflife: The elimination half-life of the carboxylic acid metabolite is approximately 2 hours following topical ocular administration.
- roouteelimination: Based on data following oral administration of alcaftadine, the carboxylic acid metabolite is primarily eliminated unchanged in the urine.
- volumedistribution:
- clearance: