-
Fesoterodine
- indication:For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
- pharmacologypharmacology:
- mechanism: Fesoterodine, once converted to its active metabolite, 5-hydroxymethyltolterodine, acts as a competitive antagonists at muscarinic receptors. This results in the inhibition of bladder contraction, decrease in detrusor pressure, and an incomplete emptying of the bladder.
- toxicity:
- absorprion:
- halflife: 7-8 hours for the active metabolite.
- roouteelimination:
- volumedistribution:
- clearance: