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Cyclandelate
- indication:Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
- pharmacologypharmacology:
- mechanism: Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle.
- toxicity: Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
- absorprion: Well absorbed following oral administration.
- halflife:
- roouteelimination:
- volumedistribution:
- clearance: