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Benzquinamide
- indication:Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously.
- pharmacologypharmacology:
- mechanism: The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
- toxicity:
- absorprion: Incomplete, with 33–39% bioavailability via the capsule and suppository routes, relative to the intramuscular route.
- halflife: 1-1.6 hours (for all formulations)
- roouteelimination:
- volumedistribution:
- clearance: