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Scopolamine
- indication:For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness.
- pharmacologypharmacology:
- mechanism: Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center).
- toxicity:
- absorprion:
- halflife:
- roouteelimination: Less than 10% of the total dose is excreted in the urine as parent and metabolites over 108 hours.
- volumedistribution:
- clearance: