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Nystatin
- indication:For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
- pharmacologypharmacology:
- mechanism: Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability.
- toxicity:
- absorprion: Nystatin is not absorbed from intact skin or mucous membrane
- halflife:
- roouteelimination:
- volumedistribution:
- clearance: