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Perflutren
- indication:Use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.
- pharmacologypharmacology:
- mechanism: Perflutren is comprised of gas-filled microspheres that are injected or infused into the body. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
- toxicity:
- absorprion:
- halflife: The mean half-life of OFP in blood 1.9 minutes
- roouteelimination:
- volumedistribution:
- clearance: