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Hexylcaine
- indication:Used as a local anesthetic for surface application, infiltration or nerve block
- pharmacologypharmacology:
- mechanism: Hexyl caine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel.
- toxicity: Symptoms of anesthetic overdose include headache, tinnitus, circumoral and tongue paresthesias, restlessness, talkativeness, facial twitching, convulsions, respiratory arrest, and cardiac depression
- absorprion:
- halflife: <10 minutes
- roouteelimination:
- volumedistribution:
- clearance: