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Isoetharine
- indication:For the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
- pharmacologypharmacology:
- mechanism: The pharmacologic effects of isoetharine are attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
- toxicity: Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects.
- absorprion:
- halflife:
- roouteelimination:
- volumedistribution:
- clearance: