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Succinylcholine
- indication:Used in surgical procedures where a rapid onset and brief duration of muscle relaxation is needed (includes intubation, endoscopies, and ECT)
- pharmacologypharmacology:
- mechanism: The mechanism of action of Succinylcholine involves what appears to be a "persistent" depolarization of the neuromuscular junction. This depolarization is caused by Succinylcholine mimicking the effect of acetylcholine but without being rapidly hydrolysed by acetylcholinesterase. This depolarization leads to desensitization.
- toxicity:
- absorprion:
- halflife:
- roouteelimination: About 10% of the drug is excreted unchanged in the urine.
- volumedistribution:
- clearance: