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Aspartame
- indication:Used as a diet supplement and sugar substitute.
- pharmacologypharmacology:
- mechanism: 180 to 200 times sweeter than sucrose, it is metabolized as a protein and its subsequent amino-acids used up in there respective mechanisms.
- toxicity: Mild gastrointestinal side effects including diarrhea have been reported.
- absorprion: Absorbed in the small intestine, aspartame is metabolized and absorbed very quickly.
- halflife: At room temperature, aspartame is most stable at pH 4.3, where its half-life is nearly 300 days. At pH 7 however, its half-life is only a few days.
- roouteelimination:
- volumedistribution:
- clearance: