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Imiglucerase
- indication:For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
- pharmacologypharmacology:
- mechanism: Imiglucerase catalyzes the hydrolysis of the glycolipid, glucocerebroside, to glucose and ceramide as part of the normal degradation pathway for membrane lipids.
- toxicity:
- absorprion:
- halflife: 3.6-10.4 min
- roouteelimination:
- volumedistribution: * 0.09 to 0.15 L/kg
- clearance: * 14.5 +/- 4.0 mL/min/kg