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Rasburicase
- indication:For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)
- pharmacologypharmacology:
- mechanism: Rasburicase catalyzes enzymatic oxidation of uric acid into an inactive and soluble metabolite (allantoin).
- toxicity:
- absorprion:
- halflife: 18 hours
- roouteelimination:
- volumedistribution: * 110 to 127 mL/kg [pediatric patients] * 75.8 to 138 mL/kg [adult patients]
- clearance: