Αναζήτηση Δραστικών

TIZANIDINE

Εμπορικές Ονομασίες

  • DRUGBANK - Tizanidine
  • indication:

    For the management of increased muscle tone associated with spasticity

  • pharmacology:

  • mechanism:

    Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agonist action at a2-adrenergic receptor sites.

  • toxicity:

  • absorprion:

  • halflife:

    2.5 hours

  • roouteelimination:

    Approximately 95% of an administered dose is metabolized.

  • volumedistribution:

    * 2.4 L/kg

  • clearance: