For treatment of inoperable adrenocortical tumours; Cushing's syndrome
Its biochemical mechanism of action is unknown, although data are available to suggest that the drug modifies the peripheral metabolism of steroids as well as directly suppressing the adrenal cortex.
About 40% oral Lysodren is absorbed
18-159 days
A variable amount of metabolite (1%-17%) is excreted in the bile and the balance is apparently stored in the tissues.