Αναζήτηση Δραστικών

LUTROPIN ALFA

ATC

Εμπορικές Ονομασίες

  • DRUGBANK - Lutropin alfa
  • indication:

    For treatment of female infertility

  • pharmacology:

  • mechanism:

    Binds to the luteinizing hormone receptor which then activates adenylate cylcase through G protein mediation. Adenylate cyclase then activates many other pathways leading to steroid hormone production and other follicle maturation processes.

  • toxicity:

  • absorprion:

  • halflife:

    4.4 hours (mammalian reticulocytes, in vitro)

  • roouteelimination:

    Total body clearance is approximately 2 to 3 L/h with less than 5 percent of the dose being excreted unchanged renally.

  • volumedistribution:

    * 10 L

  • clearance:

    * 2 – 3 L/h [healthy female following subcutaneous administration]