ZAKODIAN

UNIVADIS - ZAKODIAN /univadis/ZAKODIAN.md

ATC

Μορφές: F.C.TAB

Ημερομηνία	barcode	code	περιεχομενο	τιμή παραγωγός	χονδρική	λιανική
05/2018	2802939601017	293960101	ZAKODIAN F.C.TAB 80MG/TAB BTx30 σε blisters	3.48	3.65	05.04
05/2018	2802939602014	293960201	ZAKODIAN F.C.TAB 160MG/TAB BTx30 σε blisters	4.29	4.50	6.20
05/2018	2802939603011	293960301	ZAKODIAN F.C.TAB 320MG/TAB BTx30 σε blisters	6.67	7.00	9.65
05/2018	2802940701010	294070101	ZAKODIAN PLUS F.C.TAB (80+12,5)MG/TAB BTx14 (blister)	2.30	2.41	3.32
05/2018	2802940701027	294070102	ZAKODIAN PLUS F.C.TAB (80+12,5)MG/TAB BTx30 (blister)	3.78	3.97	5.47
05/2018	2802940702017	294070201	ZAKODIAN PLUS F.C.TAB (160+12,5)MG/TAB BTx14 (blister)	3.15	3.30	4.55
05/2018	2802940702024	294070202	ZAKODIAN PLUS F.C.TAB (160+12,5)MG/TAB BTx30 (blister)	5.14	5.39	7.43
05/2018	2802940703014	294070301	ZAKODIAN PLUS F.C.TAB (160+25)MG/TAB BTx14 (blister)	03.08	3.23	4.45
05/2018	2802940704011	294070401	ZAKODIAN PLUS F.C.TAB (320+12,5)MG/TAB BTx14 (blister)	5.21	5.47	7.54
05/2018	2802940704028	294070402	ZAKODIAN PLUS F.C.TAB (320+12,5)MG/TAB BTx30 (blister)	08.01	8.40	11.58
05/2018	2802940705018	294070501	ZAKODIAN PLUS F.C.TAB (320+25)MG/TAB BTx14 (blister)	5.36	5.62	7.75
05/2018	2802940705025	294070502	ZAKODIAN PLUS F.C.TAB (320+25)MG/TAB BTx30 (blister)	8.54	8.96	12.35

DRUGBANK - Valsartan
indication:
For the treatment of hypertension.
pharmacology:
mechanism:
Valsartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.
toxicity:
absorprion:
Absolute bioavailability = 23% with high variability
halflife:
The initial phase t1/2 &alpha; is < 1 hour while the terminal phase t1/2 &beta; is 5-9 hours.
roouteelimination:
volumedistribution:
* 17 L
clearance:
* 2 L/h [IV administration] * 4.5 L/h [heart Failure patients receiving oral administration 40 to 160 mg twice a day]