| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801980101019 | 198010101 | WARTEC CUT.SOL 0,5% FLx3ML | 9.86 | 10.34 | 14.25 |
| 05/2018 | 2801980102016 | 198010201 | WARTEC CREAM 0,15% TUBx5G | 12.51 | 13.13 | 18.09 |
For treatment of external genital warts (<i>Condyloma acuminatum</i>).
The exact mechanism of action is not well understood. It does appear, however, that it and its derivatives may bind and inhibit topoisomerase II during the late S and early G2 stage. The drug may bind and stabilize the temporary break caused by the enzyme. This disrupts the reparation of the break through which the double-stranded DNA passes, and consequently stops DNA unwinding and replication
Topical application of 0.05 mL of 0.5% podofilox solution to external genitalia did not result in detectable serum levels. Applications of 0.1 to 1.5 mL resulted in peak serum levels of 1 to 17 ng/mL one to two hours after application.
1.0 to 4.5 hours.