| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801960401016 | 196040101 | VISTAGAN EY.DRO.SOL 0.5% W/V FL x 5 ML | 1.93 | 02.03 | 2.80 |
For lowering intraocular pressure (IOP) and may be used in patients with chronic open-angle glaucoma or ocular hypertension.
Levobunolol's mechanism of action in reducing IOP is not clearly defined, but is believed to be due to a reduction of the production of aqueous humor via blockage of endogenous catecholamine-stimulated increases in cyclic adenosine monophosphate (AMP) concentrations within the ciliary processes.
Bradycardia, hypotension, bronchospasm, and acute cardiac failure, LD<sub>50</sub>=700 mg/kg (orally in rat).
80%
20 hours