| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2803117401023 | 311740102 | QUETIAPINE/SANDOZ PR.TAB 50MG/TAB BTx30 (PVC/PCTFE-Alu Blisters) | 3.37 | 3.53 | 4.87 |
| 05/2018 | 2803117401054 | 311740105 | QUETIAPINE/SANDOZ PR.TAB 50MG/TAB BTx60 (PVC/PCTFE-Alu Blisters) | 4.76 | 4.99 | 6.88 |
| 05/2018 | 2803117402020 | 311740202 | QUETIAPINE/SANDOZ PR.TAB 150MG/TAB BTx30 (PVC/PCTFE-Alu Blisters) | 13.97 | 14.65 | 20.19 |
| 05/2018 | 2803117402051 | 311740205 | QUETIAPINE/SANDOZ PR.TAB 150MG/TAB BTx60 (PVC/PCTFE-Alu Blisters) | 18.04 | 18.92 | 26.08 |
| 05/2018 | 2803117403027 | 311740302 | QUETIAPINE/SANDOZ PR.TAB 200MG/TAB BTx30 (PVC/PCTFE-Alu Blisters) | 9.40 | 9.86 | 13.59 |
| 05/2018 | 2803117403058 | 311740305 | QUETIAPINE/SANDOZ PR.TAB 200MG/TAB BTx60 (PVC/PCTFE-Alu Blisters) | 16.57 | 17.38 | 23.95 |
| 05/2018 | 2803117404024 | 311740402 | QUETIAPINE/SANDOZ PR.TAB 300MG/TAB BTx30 (PVC/PCTFE-Alu Blisters) | 14.80 | 15.52 | 21.39 |
| 05/2018 | 2803117404055 | 311740405 | QUETIAPINE/SANDOZ PR.TAB 300MG/TAB BTx60 (PVC/PCTFE-Alu Blisters) | 26.03 | 27.30 | 37.62 |
| 05/2018 | 2803117405021 | 311740502 | QUETIAPINE/SANDOZ PR.TAB 400MG/TAB BTx30 (PVC/PCTFE-Alu Blisters) | 24.60 | 25.81 | 35.56 |
| 05/2018 | 2803117405052 | 311740505 | QUETIAPINE/SANDOZ PR.TAB 400MG/TAB BTx60 (PVC/PCTFE-Alu Blisters) | 43.31 | 45.43 | 62.60 |
For the treatment of schizophrenia and related psychotic disorders.
Quetiapine's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex. Antagonism at D2 receptors relieves positive symptoms while antagonism at 5HT2A receptors relieves negative symptoms of schizophrenia.
Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.
Rapidly and well absorbed.
6 hours
Elimination of quetiapine is mainly via hepatic metabolism. Following a single oral dose of 14C-quetiapine, less than 1% of the administered dose was excreted as unchanged drug, indicating that quetiapine is highly metabolized. Approximately 73% and 20% of the dose was recovered in the urine and feces, respectively.
* 10±4 L/kg