| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2802852701016 | 285270101 | ONIRIA OR.SO.D 10MG/ML BOTTLE x 30 ML | 2.35 | 2.47 | 3.40 |
For the short-term treatment of insomnia.
Zolpidem modulates the alpha-subunit, known as the benzodiazepine receptor, within the GABA<sub>A</sub> receptor chloride channel macromolecular complex. Unlike the benzodiazepines, which non-selectively interact with all three alpha-receptor subtypes, Zolpidem preferentially binds to the alpha-1 receptor.
Oral (male rat) LD<sub>50</sub> = 695 mg/kg. Symptoms of overdose include impairment of consciousness ranging from somnolence to light coma.
Zolpidem is rapidly absorbed from the GI tract.
2.6 hours
Zolpidem tartrate tablets are converted to inactive metabolites that are eliminated primarily by renal excretion.