| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2802660001018 | 266000101 | MEDITHYROX TAB 25MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.31 | 1.37 | 1.89 |
| 05/2018 | 2802660001025 | 266000102 | MEDITHYROX TAB 25MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.31 | 1.37 | 1.89 |
| 05/2018 | 2802660002015 | 266000201 | MEDITHYROX TAB 50MC/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.32 | 1.38 | 1.90 |
| 05/2018 | 2802660002022 | 266000202 | MEDITHYROX TAB 50MC/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.32 | 1.38 | 1.90 |
| 05/2018 | 2802660003012 | 266000301 | MEDITHYROX TAB 75MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.39 | 1.92 |
| 05/2018 | 2802660003029 | 266000302 | MEDITHYROX TAB 75MCG/TAB BTx30 (2 BLISTERS X15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.39 | 1.92 |
| 05/2018 | 2802660004019 | 266000401 | MEDITHYROX TAB 88MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.39 | 1.92 |
| 05/2018 | 2802660004026 | 266000402 | MEDITHYROX TAB 88MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.39 | 1.92 |
| 05/2018 | 2802660005016 | 266000501 | MEDITHYROX TAB 100MC/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.40 | 1.93 |
| 05/2018 | 2802660005023 | 266000502 | MEDITHYROX TAB 100MC/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.33 | 1.40 | 1.93 |
| 05/2018 | 2802660006013 | 266000601 | MEDITHYROX TAB 112MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.34 | 1.41 | 1.94 |
| 05/2018 | 2802660006020 | 266000602 | MEDITHYROX TAB 112MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.34 | 1.41 | 1.94 |
| 05/2018 | 2802660007010 | 266000701 | MEDITHYROX TAB 125MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.35 | 1.42 | 1.96 |
| 05/2018 | 2802660007027 | 266000702 | MEDITHYROX TAB 125MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.35 | 1.42 | 1.96 |
| 05/2018 | 2802660008017 | 266000801 | MEDITHYROX TAB 137MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.35 | 1.42 | 1.96 |
| 05/2018 | 2802660008024 | 266000802 | MEDITHYROX TAB 137MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.35 | 1.42 | 1.96 |
| 05/2018 | 2802660009014 | 266000901 | MEDITHYROX TAB 150MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL) σε BLISTERS PVC/ALUM FOIL) | 1.36 | 1.43 | 1.97 |
| 05/2018 | 2802660009021 | 266000902 | MEDITHYROX TAB 150MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL) σε BLISTERS PVC/ALUM FOIL) | 1.36 | 1.43 | 1.97 |
| 05/2018 | 2802660010010 | 266001001 | MEDITHYROX TAB 175MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL) σε BLISTERS PVC/ALUM FOIL) | 1.37 | 1.44 | 1.98 |
| 05/2018 | 2802660010027 | 266001002 | MEDITHYROX TAB 175MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL) σε BLISTERS PVC/ALUM FOIL) | 1.37 | 1.44 | 1.98 |
| 05/2018 | 2802660011017 | 266001101 | MEDITHYROX TAB 200MC/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.38 | 1.45 | 2.00 |
| 05/2018 | 2802660011024 | 266001102 | MEDITHYROX TAB 200MC/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.38 | 1.45 | 2.00 |
| 05/2018 | 2802660012014 | 266001201 | MEDITHYROX TAB 12MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.30 | 1.36 | 1.88 |
| 05/2018 | 2802660012021 | 266001202 | MEDITHYROX TAB 12MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.30 | 1.36 | 1.88 |
| 05/2018 | 2802660013011 | 266001301 | MEDITHYROX TAB 62MCG/TAB BTx30 (BLIST 3x10) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.32 | 1.38 | 1.90 |
| 05/2018 | 2802660013028 | 266001302 | MEDITHYROX TAB 62MCG/TAB BTx30 (2 BLISTERS x15) σε BLISTERS PVC/ALUM FOIL σε BLISTERS PVC/ALUM FOIL | 1.32 | 1.38 | 1.90 |
Used to lower high cholesterol levels in the blood.
Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route into the feces, with a resulting reduction in serum cholesterol and LDL. Dextrothyroxine has no significant effect on high-density lipoproteins (HDL).
Symptoms of dextrothyroxine overdose are unknown.
For use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.
Levothyroxine acts like the endogenous thyroid hormone thyroxine (T<sub>4</sub>, a tetra-iodinated tyrosine derivative). In the liver and kidney, T<sub>4</sub> is converted to T<sub>3</sub>, the active metabolite. In order to increase solubility, the thyroid hormones attach to thyroid hormone binding proteins, thyroxin-binding globulin, and thyroxin-binding prealbumin (transthyretin). Transport and binding to thyroid hormone receptors in the cytoplasm and nucleus then takes place. Thus by acting as a replacement for natural thyroxine, symptoms of thyroxine deficiency are relieved.
LD<sub>50</sub>=20 mg/kg (orally in rat). Hypermetabolic state indistinguishable from thyrotoxicosis of endogenous origin. Symptoms of thyrotoxicosis include weight loss, increased appetite, palpitations, nervousness, diarrhea, abdominal cramps, sweating, tachycardia, increased pulse and blood pressure, cardiac arrhythmias, tremors, insomnia, heat intolerance, fever, and menstrual irregularities.
Bioavailability varies from 48% to 80%. Human studies have confirmed the importance of an intact jejunum and ileum for levothyroxine absorption and have shown some absorption from the duodenum.
T<sub>4</sub>, 6 to 7 days. T<sub>3</sub>, 1 to 2 days.
Thyroid hormones are primarily eliminated by the kidneys.