| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2803049501013 | 304950101 | LIZEDIA F.C.TAB 600MG/TAB BTx10 TABS (PA/AL/PVC-AL Foil Blisters) | 141.31 | 148.23 | 182.27 |
| 05/2018 | 2803049501037 | 304950103 | LIZEDIA F.C.TAB 600MG/TAB BTx30 TABS (PA/AL/PVC-AL Foil Blisters) | 385.53 | 391.32 | 456.28 |
| 05/2018 | 2803049502010 | 304950201 | LIZEDIA SOL.IV.INF 2MG/ML BTx1 BAG x300ml | 19.67 | 20.63 | 28.43 |
For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant <i>Enterococcus faecium</i>, <i>Staphylococcal aureus</i> (methicillin resistant and susceptible strains), <i>Streptococcus pneumoniae</i>, <i>Streptococcus pyogenes</i>, <i>Streptococcus agalactiae</i>.
Linezolid is a synthetic antibacterial agent of the oxazolidinone class of antibiotics. It has in vitro activity against aerobic Gram positive bacteria, certain Gram negative bacteria and anaerobic microorganisms. It selectively inhibits bacterial protein synthesis through binding to sites on the bacterial ribosome and prevents the formation of a functional 70S-initiation complex. Specifically, linezolid binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, which is an essential component of the bacterial translation process. The results of time-kill studies have shown linezolid to be bacteriostatic against enterococci and staphylococci. For streptococci, linezolid was found to be bactericidal for the majority of strains. Linezolid is also a reversible, nonselective inhibitor of monoamine oxidase. Therefore, linezolid has the potential for interaction with adrenergic and serotonergic agents.
Clinical signs of acute toxicity lead to decreased activity, ataxia, vomiting and tremors.
Linezolid is rapidly and extensively absorbed after oral dosing. Maximum plasma concentrations are reached approximately 1 to 2 hours after dosing, and the absolute bioavailability is approximately 100%.
4.5-5.5 hours
* 40 to 50 L [healthy adult volunteers]