| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801098201014 | 109820101 | LADOSE CAPS 20MG/CAP ΒΤ x 12 | 3.62 | 3.79 | 5.23 |
| 05/2018 | 2801098202028 | 109820202 | LADOSE ORAL.SOL 20MG/5ML FLx70 ML | 4.35 | 4.56 | 6.29 |
| 05/2018 | 2801098203025 | 109820302 | LADOSE DISP.TAB 20MG/TAB BTx28 (BLIST 2x14) | 7.56 | 7.93 | 10.93 |
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Metabolized to norfluoxetine, fluoxetine is a selective serotonin-reuptake inhibitor (SSRI), it blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT<sub>1A</sub> autoreceptors. SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD<sub>50</sub>=284mg/kg (orally in mice).
72%
1 to 3 days
The primary route of elimination appears to be hepatic metabolism to inactive metabolites excreted by the kidney.