| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2800129704012 | 12970401 | INDERAL F.C.TAB 40MG/TAB ΒΤx30 (BLIST 1x30) | 1.13 | 1.19 | 1.64 |
For the prophylaxis of migraine.
Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension.
Symptoms of overdose include bradycardia, cardiac failure, hypotension, and brochospasm. LD<sub>50</sub>=565 mg/kg (orally in mice).
Propranolol is almost completely absorbed from the GI tract; however, plasma concentrations attained are quite variable among individuals.
4 hours
Propranolol is extensively metabolized with most metabolites appearing in the urine.
* 4 L