| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801601901011 | 160190101 | HYPNOMIDATE INJ.SOL 20 MG/10ML AMP BTx 5 AMPS x 10 ML | 2.77 | 2.91 | 04.01 |
Used in the induction of general anesthesia.
Etomidate binds at a distinct binding site associated with a Cl<sup>-</sup> ionopore at the GABA<sub>A</sub> receptor, increasing the duration of time for which the Cl<sup>-</sup> ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
75 minutes.
Approximately 75% of the administered dose is excreted in the urine during the first day after injection.