| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2802882501020 | 288250102 | EFIENT F.C.TAB 5MG/TAB BTx28 σε BLISTERS (ALU) (ALU) | 32.23 | 33.81 | 46.59 |
| 05/2018 | 2802882502027 | 288250202 | EFIENT F.C.TAB 10MG/TAB BTx28 σε BLISTERS (ALU) (ALU) | 35.50 | 37.24 | 51.31 |
For use/treatment in strokes and coronary artery disease.
Prasugrel is an thienopyridine which inhibits ADP receptors by irreversibly acting on the P2Y12 receptor on platelets. The active metabolite of prasugrel prevents binding of adenosine diphosphate (ADP) to its platelet receptor, impairing the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Prasugrel is proposed to have a similar mechanism of action to clopidogrel.
LD50 (rat) 1,000 - 2,000 mg/kg; LD50 (rabbit) > 1,000 mg/kg
The active metabolite has an elimination half-life of about 7 hours (range 2-15 hours).