| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2802468001029 | 246800102 | DAGRILAN CAPS 20MG/CAP BT x 30 (BLIST 3x10) | 5.31 | 5.57 | 7.67 |
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Metabolized to norfluoxetine, fluoxetine is a selective serotonin-reuptake inhibitor (SSRI), it blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT<sub>1A</sub> autoreceptors. SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD<sub>50</sub>=284mg/kg (orally in mice).
72%
1 to 3 days
The primary route of elimination appears to be hepatic metabolism to inactive metabolites excreted by the kidney.