| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801964101011 | 196410101 | CLEXANE INJ.SOL 2000ANTI-XA IU/0,2ML BTx2PF.SYR.x0,2ML | 02.02 | 2.12 | 2.92 |
| 05/2018 | 2801964102018 | 196410201 | CLEXANE INJ.SOL 4000ANTI-XA IU/0,4ML BTx2 PF.SYR.x0,4 ML | 3.76 | 3.94 | 5.43 |
| 05/2018 | 2801964103039 | 196410303 | CLEXANE INJ.SOL 6000anti-XA IU/0,6ml BTx10 PF.SYRx0,6 ML | 25.55 | 26.80 | 36.93 |
| 05/2018 | 2801964104050 | 196410405 | CLEXANE INJ.SOL 8000anti-XA IU/0,8ml BTx10 PF.SYR.x0.8 ML | 32.58 | 34.18 | 47.10 |
| 05/2018 | 2801964110020 | 196411002 | CLEXANE INJ.SOL 12000anti-XaIU/0,8ML PF.SYR BT x10PF.SYR. x0,8ML | 58.44 | 61.30 | 77.97 |
| 05/2018 | 2801964111027 | 196411102 | CLEXANE INJ.SOL 15000anti-XaIU/1,0ML PF.SYR BT x10PF.SYR.x1,0ML | 67.58 | 70.89 | 90.17 |
For anticoagulant therapy in prophylaxis and treatment of venous thrombosis and its extension, for prevention of post-operative deep venous thrombosis and pulmonary embolism and for the prevention of clotting in arterial and cardiac surgery.
The mechanism of action of heparin is antithrombin-dependent. It acts mainly by accelerating the rate of the neutralization of certain activated coagulation factors by antithrombin, but other mechanisms may also be involved. The antithrombotic effect of heparin is well correlated to the inhibition of factor Xa. Heparin interacts with antithrombin III, prothrombin and factor X.
Heparin sodium - Mouse, median lethal dose greater than 5000 mg/kg. Another side effect is heparin induced thrombocytopenia (HIT syndrome). HIT is caused by an immunological reaction that makes platelets form clots within the blood vessels, thereby using up coagulation factors
Some oral absorption but lack of anticoagulant effect. Rapidly taken up by endothelial cells with remainder bound to plasma proteins.
1.5 hours