| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801122001016 | 112200101 | CANESTEN VAG.TAB 0,5G/TAB BTx1TAB+1APPLICATEUR | 2.61 | 2.74 | 3.77 |
| 05/2018 | 2801122002020 | 112200202 | CANESTEN VAG.TAB 0,1G/TAB BTx6(AL FORM PACK)+ 1 APPLICATEUR 1 APPLICATEUR | 2.25 | 2.36 | 3.25 |
| 05/2018 | 2801122005014 | 112200501 | CANESTEN VAG.CR 2% TUB x 20 G + 3 APPLICATEUR 3 APPLICATEUR | 3.22 | 3.38 | 4.66 |
For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.
Clotrimazole interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. In this way, clotrimazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Clotrimazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.
Poorly and erratically absorbed orally, minimal vaginal or topical absorption.
2 hours