| Ημερομηνία | barcode | code | περιεχομενο | τιμή παραγωγός | χονδρική | λιανική |
|---|---|---|---|---|---|---|
| 05/2018 | 2801165701010 | 116570101 | ADALAT S.R.F.C.TA 20MG/TAB ΒΤ x 30(BLIST 3x10) | 2.25 | 2.36 | 3.25 |
| 05/2018 | 2801165702017 | 116570201 | ADALAT SOFT.CAPS 5MG/CAP ΒΤx50 (BLISTER 5x10) P.P. (BLISTER 5x10) P.P. | 2.13 | 2.23 | 03.08 |
| 05/2018 | 2801165703014 | 116570301 | ADALAT SOFT.CAPS 10MG/CAP ΒΤx50 (BLISTER 5x10) P.P | 1.75 | 1.84 | 2.53 |
| 05/2018 | 2801165704011 | 116570401 | ADALAT SOL.INF 5mg/50ml VIAL BTx1 VIALx50 ML +1 ΣΥΡ.(PERFUSOR)+1 ΣΩΛ.ΕΓΧ.(PERFUSOR) +1 ΣΥΡ.(PERFUSOR)+1 ΣΩΛ.ΕΓΧ.(PERFUSOR) | 9.54 | 10.01 | 13.79 |
| 05/2018 | 2801165706015 | 116570601 | ADALAT CR CON.R.TAB 30MG/TAB BT x28 (BLIST 2x14) | 3.47 | 3.64 | 05.01 |
| 05/2018 | 2801165707012 | 116570701 | ADALAT CR CON.R.TAB CR.TAB 60MG/TAB BTx28 (BLIST 2x14) | 5.61 | 5.88 | 8.10 |
| 05/2018 | 2801165713013 | 116571301 | ADALAT CR CON.R.TAB 20MG/TAB BT X 28 (BL.2 X 14) | 4.22 | 4.43 | 6.10 |
For the management of vasospastic angina, chronic stable angina and hypertension.
Nifedipine inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel. The decrease in intracellular calcium inhibits the contractile processes of smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD<sub>50</sub>=494 mg/kg (orally in mice); LD<sub>50</sub>=1022 mg/kg (orally in rats)
Rapidly and fully absorbed following oral administration.
2 hours
Nifedipine is extensively metabolized to highly water-soluble, inactive metabolites accounting for 60 to 80% of the dose excreted in the urine. The remainder is excreted in the feces in metabolized form, most likely as a result of biliary excretion.