LEVEL 4 J05AE02

Δραστικές

INDINAVIR

Φάρμακα

  • DRUGBANK - Indinavir
  • indication:

    Indinavir is an antiretroviral drug for the treatment of HIV infection.

  • pharmacology:

  • mechanism:

    Indinavir inhibits the HIV viral protease enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

  • toxicity:

    Symptoms of overdose include myocardial infarction and angina pectoris.

  • absorprion:

    Rapidly absorbed

  • halflife:

    1.8 (± 0.4) hours

  • roouteelimination:

    Less than 20% of indinavir is excreted unchanged in the urine.

  • volumedistribution:

  • clearance: