Used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.
Overdosage of cephalosporins can cause cerebral irritation leading to convulsions.
Rapidly absorbed following oral administration.
Ceftibuten is excreted in the urine; 95% of the administered radioactivity was recovered either in urine or feces.
* 0.21 L/kg [adult subjects] * 0.5 L/kg [fasting pediatric patients]