LEVEL 4 A07AA02

Δραστικές

Φάρμακα

  • DRUGBANK - Nystatin
  • indication:

    For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

  • pharmacology:

  • mechanism:

    Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability.

  • toxicity:

  • absorprion:

    Nystatin is not absorbed from intact skin or mucous membrane

  • halflife:

  • roouteelimination:

  • volumedistribution:

  • clearance: